Top 200 Drugs Podcast – Drugs 31-35

On this episode of the Real Life Pharmacology podcast, I discuss drugs 31-35 of the top 200 drugs.

Ethinyl estradiol/drospirenone is a combined oral contraceptive used for birth control purposes.

Hydralazine is a direct vasodilatory that can be used for hypertension and heart failure.

Benztropine is an older anticholinergic medication originally indicated for Parkinson’s disease but most commonly used to manage EPS symptoms from dopamine-blocking agents such as antipsychotics.

Tussionex is a combination medication of chlorpheniramine and hydrocodone. It is used to help alleviate cough.

Paroxetine is an SSRI used for the treatment of depression, anxiety, and other psychiatric disorders.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Pharmacy Technician Study Guide by Meded101

Top 10 SSRI Drug Interactions Podcast

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In this podcast episode, I discuss how to navigate SSRI drug interactions and identify some of the most common medications that have additive serotonergic activity.

SSRIs have antiplatelet activity. I discuss how to navigate using other medications that may increase bleed risk in combination with SSRIs.

Paroxetine and fluoxetine inhibit CYP2D6 I discuss how this can affect the benefits of tamoxifen therapy.

Fluvoxamine is a nasty medication with regard to the number of and significance of drug interactions. I outline important fluvoxamine interactions in this podcast episode.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

Support The Podcast and Check Out These Amazing Resources!

NAPLEX Study Materials

BCPS Study Materials

BCACP Study Materials

BCGP Study Materials

BCMTMS Study Materials

Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Pharmacy Technician Study Guide by Meded101

Tamoxifen Pharmacology Podcast

On this podcast episode, I discuss tamoxifen pharmacology, adverse effects, drug interaction, and much more.

Tamoxifen is converted to a more active compound in the body by CYP2D6.

CYP2D6 inhibitors such as paroxetine, fluoxetine, or bupropion can essentially reduce the effectiveness of tamoxifen.

Hot flashes are a common adverse effect of tamoxifen and I discuss a few pharmacologic options to manage this adverse effect.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

Support The Podcast and Check Out These Amazing Resources!

NAPLEX Study Materials

BCPS Study Materials

BCACP Study Materials

BCGP Study Materials

BCMTMS Study Materials

Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Pharmacy Technician Study Guide by Meded101

Paroxetine Pharmacology

Paroxetine (Paxil) is an SSRI that can be used in the management of depression. I discuss more on paroxetine pharmacology in this episode.

Because paroxetine has some modest anticholinergic effects, it does show up on the Beers list as a potentially inappropriate medication.

By inhibiting CYP2D6, paroxetine can have numerous drug interactions. Drugs like atomoxetine, aripiprazole, and metoclopramide can all have their concentrations increased.

Tamoxifen is activated by CYP2D6 and paroxetine can ultimately reduce the effectiveness of the medication.

I discuss important drug interactions on the podcast, be sure to check out my latest project which is a 200+ page book on managing drug interactions in primary care.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!