Tag: nitrofurantoin

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Top 200 Drugs Podcast – Medications 56-60

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This episode is sponsored by Freed – Freed is an amazing time saver for busy healthcare professionals! It listens, transcribes, and writes medical notes for you! Go check them out and support our sponsor!

In this episode, we highlight some of the most important clinical pearls on the following medications; nitrofurantoin, fentanyl patches, isosorbide mononitrate, fluoxetine, and triamcinolone.

Nitrofurantoin is an antibiotic used for UTIs. We need to be careful with this medication in patients with CKD.

Fentanyl is an opioid. There are many clinical quirks with fentanyl patches. For a full rundown, check out this previous podcast episode.

Isosorbide mononitrate is a nitrate medication so we need to be careful with the use of PDE-5 inhibitors.

Fluoxetine is an SSRI. It has a longer half-life than most SSRIs. I discuss what that means in this episode.

Triamcinolone (topical) is most frequently used for redness, itching, and skin irritation.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Nitrofurantoin Pharmacology

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On this episode I breakdown nitrofurantoin pharmacology. Nitrofurantoin is an antibiotic that is used in the treatment of UTI’s.

Nitrofurantoin has activity by creating reactive metabolites that can disrupt protein synthesis and ultimately kills the bacteria causing the infection.

It is important to remember with nitrofurantoin, that in the setting of systemic infection and/or kidney involvement, the drug may not be very effective.

Nitrofurantoin can potentially reduce the effectiveness of certain vaccines. Be sure to look this up prior to administration.

Nitrofurantoin can cause pulmonary symptoms as well as neuropathy. This is very important to monitor for.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!