Tag: HIV

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Top 200 Drugs Podcast – Medications 141-145

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On this top 200 drugs podcast, we are covering medications 141-145. Raltegravir, ustekinumab, meloxicam, infliximab, and Nighttime Cold and Flu are the medications that are covered on this episode.

Raltegravir is an integrase inhibitor that is used to manage HIV infection and may also be used for post-exposure prophylaxis.

Ustekinumab is a monoclonal antibody that can help reduce inflammation by binding interleukins.

Meloxicam is an NSAID used for pain and anti-inflammatory purposes. GI bleeding risk is a top adverse effect to monitor for.

Infliximab is a monoclonal antibody that can be used for autoimmune disorders such as psoriatic arthritis, rheumatoid arthritis, ulcerative colitis, and Crohn’s disease.

Nighttime Cold and Flu medication is a combination product that often includes acetaminophen, dextromethorphan, and doxylamine.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Abacavir Pharmacology

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Abacavir is a nucleoside reverse transcriptase inhibitor used in the management of HIV.

In patients who have the HLA-B*5701 allele, they are at much greater risk for hypersensitivity reactions.

Lactic acidosis and hepatomegaly are potential complications with the use of abacavir.

While abacavir is not known for a large number of drug interactions, I discuss a few that you have a chance to run into.

I discuss important drug interactions on the podcast, be sure to check out my latest project which is a 200+ page book on managing drug interactions in primary care.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Dolutegravir

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Dolutegravir is an integrase inhibitor that is used in the management of HIV infection/

Carbamazepine along with other enzyme inducers can substantially lower the concentrations of dolutegravir.

Dolutegravir can potentially increase blood sugars, this should be closely monitored in our patients with diabetes.

CNS adverse effects like insomnia and dizziness can happen with dolutegravir.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!