Top 200 Drugs Podcast – Medications 91-95

On this episode of the Real Life Pharmacology Podcast, I cover 5 more medications of the top 200.

Fenofibrate is a medication used primarily to reduce triglycerides. This medication differs from statins which tend to focus on LDL management.

Doxazosin is an alpha-blocker. The primary indications of doxazosin are hypertension and BPH.

Naproxen is an NSAID. Of all the NSAIDs, naproxen is one of the lower-risk agents with regard to cardiovascular risk.

Spironolactone is an aldosterone antagonist and also classified as a potassium sparing diuretic.

Memantine is an NMDA antagonist that is indicated for the management of Alzheimer’s dementia.

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Fenofibrate Pharmacology Podcast Episode 310

On this podcast episode, I discuss fenofibrate pharmacology, adverse effects, kinetics, drug interactions, and much more!

Fenofibrate is typically only used for hypertriglyceridemia. The primary risk of hypertriglyceridemia is pancreatitis so we treat these levels because of this risk.

LFTs elevation has been associated with fenofibrate use as well as myopathy. In the presence of myopathy, checking CPK may be considered.

Fenofibrate is a weak CYP2C9 inhibitor. Warfarin and phenytoin are two important medications that may be affected by the use of fenofibrate.

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