Top 200 Drugs – Medications 166-170

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On this episode of the Top 200 Drugs podcast from Real Life Pharmacology, we cover Percocet, Epogen, quetiapine, glimepiride, and tirzepatide. These are drugs 166-170.

Percocet is a combination analgesic. It contains acetaminophen and oxycodone. Pay attention to acetaminophen intake from all sources when patients are on this medication.

Epogen (epoetin alfa) stimulates the production of red blood cells. This medication can be useful in treating anemia.

Quetiapine (Seroquel) is an antipsychotic. It is often used in patients with hallucinations and delusions associated with Parkinson’s disease because it has a lower potential to block dopamine receptors compared to other antipsychotics.

Glimepiride is a sulfonylurea. This medication stimulates the release of insulin which can help lower blood sugars in diabetes.

Tirzepatide (Mounjaro) is a combination GIP and GLP-1 receptor agonist that can be used for weight loss and the treatment of diabetes.

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Epoetin Alfa Pharmacology

Epoetin alfa is essential exogenous erythropoetin which can stimulate the production of red blood cells.

It is critical to ensure adequate iron stores when using EPO.

Risks for blood clots, strokes and heart attacks are critical to recognize with the use of epoetin.

Dosage adjustments with epoetin are typically made with respect to the amount of change in hemoglobin. I discuss this further in the podcast.

I discuss important drug interactions on the podcast, be sure to check out my latest project which is a 200+ page book on managing drug interactions in primary care.

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