Top 200 Drugs Podcast – Medications 86-90

On this episode of the Real Life Pharmacology podcast, we cover 5 more medications in the top 200.

Metronidazole is an antibiotic for infection. One of the most common complaints from patients involves reporting of a metallic taste in the mouth.

Levetiracetam is an anti-seizure medication. Sedation, dizziness, and other adverse effects of the central nervous system are the most common complications.

Colchicine is a gout medication. The most memorable side effect associated with this medication is diarrhea.

Olanzapine is an antipsychotic. Olanzapine carries a higher risk for metabolic syndrome compared to other antipsychotics.

Dutasteride is a 5 alpha-reductase inhibitor that is indicated for the treatment of BPH.

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Dutasteride (Avodart) Pharmacology Podcast

Dutasteride (Avodart) is a 5-alpha-reductase inhibitor. I discuss the pharmacology, adverse effects, and drug interactions on this podcast.

Dutasteride reduces the size of the prostate over time. It takes a significant amount of time to provide symptom relief (usually at least 3-6 months).

Dutasteride is broken down by CYP3A4 to a minor extent which means that strong CYP3A4 inhibitors may increase drug concentrations.

When using dutasteride for BPH, remember to review the medication list for drugs that can cause urinary retention such as anticholintiercs and alpha-agonists.

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