Tag: drug interactions

Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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August 18, 2022August 11, 2022

Lurasidone Pharmacology

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On this podcast episode, I discuss lurasidone pharmacology, adverse effects, and drug interactions.

CYP3A4 is an important enzyme in the breakdown of lurasidone. I discuss this further on this episode.

Lurasidone is best taken with food as this enhances absorption and helps improve drug concentrations.

Lurasidone tends to have a lower risk for metabolic syndrome compared to other antipsychotics which is a nice advantage.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

July 28, 2022July 15, 2022

Olmesartan Pharmacology

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On this episode, I discuss olmesartan (Benicar) pharmacology, adverse effects, drug interactions, and pharmacokinetics.

Olmesartan can cause a unique GI adverse effect called enteropathy. I discuss this on this podcast episode.

Important monitoring parameters for olmesartan include potassium, renal function, and blood pressure.

Olmesartan has a longer half-life than losartan. I discuss how this might be advantageous in clinical practice.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

July 21, 2022July 13, 2022

Desvenlafaxine Pharmacology

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On this episode, I discuss desvenlafaxine pharmacology, adverse effects, pharmacokinetics, and drug interactions.

Desvenlafaxine is a serotonin and norepinephrine reuptake inhibitor that can be used for depression.

Renal elimination is an important method of deactivation of desvenlafaxine. Dose adjustments may be recommended as renal function drops below 50 mls/min.

Withdrawal syndrome due is a risk with desvenlafaxine as it has a significantly short half-life.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

July 14, 2022July 8, 2022

Pramipexole (Mirapex) Pharmacology

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Pramipexole (Mirapex) is a dopamine agonist that can be used in Parkinson’s disease and Restless Legs Syndrome.

Dopamine agonists like pramipexole can worsen psychiatric symptoms in some patients by causing hallucinations, and obsessive/compulsive symptoms.

Nausea, vomiting, hypotension, and fatigue are the most common adverse effects of pramipexole.

Pramipexole is primarily eliminated through the urine. I discuss how this matters clinically in greater detail in this podcast episode.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

July 7, 2022June 27, 2022

Prednisolone Pharmacology

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I mentioned prednisolone to prednisone conversion in this podcast. Please go check out Pyrls.com for a free steroid conversion downloadable PDF with a free account!

On this episode, I discuss prednisolone (Orapred, Pediapred) pharmacology, adverse effects, practice pearls, and drug interactions.

Prednisolone is a systemic corticosteroid that can cause insomnia, elevations in blood sugars, and numerous effects if used long-term.

CYP3A4 is an important enzyme in the breakdown of prednisolone. Inhibitors or inducers may raise or lower drug levels respectively.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

June 30, 2022June 27, 2022

Bisoprolol (Zebeta) Pharmacology

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On this episode, I discuss bisoprolol (Zebeta) pharmacology, adverse effects, drug interactions, and other important clinical pearls.

Bisoprolol is a beta-1 selective antagonist that can be used for atrial fibrillation, angina, and other cardiovascular indications.

It is important to remember that bisoprolol and other beta-blockers are not considered first-line agents for hypertension alone.

Beta-receptor selectivity does start to disappear with bisoprolol as you get to higher dosages. I discuss this further in the podcast.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)