Tag: diabetes

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January 9, 2025January 6, 2025

Top 200 Drugs – Medications 156-160

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Welcome back to the Real Life Pharmacology podcast! We are on the home stretch of the top 200 medications. This is meant to be a quicker refresher of some of the most important drugs you’ll come across in practice. Please be sure to go search the archives at RealLifePharmacology.com if you are looking for more information on one specific medication. We have over 300 individual episodes on specific drugs!

On this episode of the Top 200 medications, we’ve covered the medications below.

Niaspan (niacin) is vitamin B3 and may be used in patients who fail other therapies for triglyceride management.

Uroxatral (alfuzosin) is a selective alpha-blocker that can be helpful in relieving urinary retention symptoms in BPH.

Biaxin (clarithromycin) is a macrolide antibiotic that is notorious for many drug interactions because it inhibits CYP3A4.

Zomig (zolmitriptan) is a “triptan” medication that can be used for the acute relief of migraine headaches.

Invokana (canagliflozin) was one of the first SGLT2 inhibitors invented that can be used to lower blood sugar in type 2 diabetes.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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September 26, 2024September 23, 2024

Top 200 Drugs Podcast – Medications 81-85

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On this episode of the Real Life Pharmacology podcast, I cover medications 81 through 85 on the top 200 drug list.

Famotidine is an H2 blocker. H2 blockers are less potent than PPIs but can be used to manage heartburn symptoms.

Aspirin is technically an NSAID but is primarily used for cardioprophylaxis purposes.

Senna is a stimulant laxative. I often see this medication used with opioids to help manage opioid-induced constipation.

Novolog is a rapid acting insulin used to bring down post prandial blood sugars. I discuss sliding scale insulin and other concepts with this medication.

Baclofen is a skeletal muscle relaxant. It has central nervous system depressant effects which can be especially problematic in elderly patients.

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May 23, 2024May 21, 2024

Continuous Glucose Monitors Podcast

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Continuous Glucose Monitors (CGMs) are becoming an important tool in the management of diabetes. I break down some of the most common clinical practice pearls you should know.

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February 22, 2024February 28, 2024

Teplizumab For Diabetes Episode 315 – Real Life Pharmacology Podcast

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Teplizumab is a relatively new agent that helps delay the progression of type 1 diabetes. It slows the rate of beta-cell destruction in the pancreas.

Teplizumab is associated with cytokine release syndrome which can result in flu-like symptoms of fever, aches, and headache.

Cytokine release syndrome due to teplizumab can be reduced by using appropriate pretreatment medications. Those medications can include analgesics, antihistamines, and/or antiemetics.

Teplizumab is associated with suppressing the immune system so it is ideal to get vaccinations completed before using this medication. I go over the specific recommendations in the podcast episode.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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February 1, 2024January 30, 2024

Insulin Aspart (Novolog) Pharmacology Podcast Episode 312

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On this podcast episode, I discuss insulin aspart pharmacology, adverse effects, drug interactions, and much more.

Insulin apart is a rapid acting insulin product meant to bring down blood sugars quickly (most often after meals).

It is important to remember a couple of medications that may counteract the effects of insulin and apart and raise blood sugar. I talk about corticosteroids and thiazide diuretics in the drug interaction section.

Fiasp is a slightly modified insulin aspart molecule that allows for quicker absorption. This quicker absorption will allow for blood sugars to come down sooner than the Novolog formulation.

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August 31, 2023August 29, 2023

Insulin Lispro (Humalog) Pharmacology Podcast

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On this podcast episode, I discuss the pharmacology, adverse effects, and drug interactions of insulin lispro (Humalog).

I spend some time on this podcast episode discussing carb ratios and sliding scale insulin when using insulin lispro.

Potassium is critical to monitor in diabetic ketoacidosis as insulin therapy can cause significant hypokalemia.

Sliding-scale insulin lispro is discouraged in the overwhelming majority of situations. Ideally, we should be more proactive about insulin administration to reduce the risk of hyperglycemia spikes.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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June 15, 2023June 9, 2023

Bexagliflozin Pharmacology Podcast

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On this podcast episode, I discuss bexagliflozin pharmacology, adverse effects, drug interactions, and much more.

I wasn’t wowed by the A1C reduction of this medication. I get into the specifics on bexagliflozin in the podcast episode.

SGLT2 inhibitors like bexagliflozin increase the glucose in the urine which can facilitate the growth of bacteria and fungi in the genitourinary tract.

Limb amputation and euglycemic DKA are two rare, reported adverse effects to be aware of with the use of bexagliflozin.

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April 6, 2023April 6, 2023

Exenatide Pharmacology Podcast

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On this podcast episode, I discuss exenatide pharmacology, adverse effects, drug interactions, and much more!

Exenatide has an immediate release formulation (Byetta) and a long acting formulation (Bydureon). I discuss the differences in this podcast episode.

Byetta use has fallen out of favor due to frequent dosing, patient inconvenience and needing to time the dose 60 minutes prior to meals.

I discuss the risk of pancreatitis related to GLP-1 agonists like exenatide in this podcast episode.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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