Top 200 Drugs Podcast – Medications 56-60

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In this episode, we highlight some of the most important clinical pearls on the following medications; nitrofurantoin, fentanyl patches, isosorbide mononitrate, fluoxetine, and triamcinolone.

Nitrofurantoin is an antibiotic used for UTIs. We need to be careful with this medication in patients with CKD.

Fentanyl is an opioid. There are many clinical quirks with fentanyl patches. For a full rundown, check out this previous podcast episode.

Isosorbide mononitrate is a nitrate medication so we need to be careful with the use of PDE-5 inhibitors.

Fluoxetine is an SSRI. It has a longer half-life than most SSRIs. I discuss what that means in this episode.

Triamcinolone (topical) is most frequently used for redness, itching, and skin irritation.

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Dexamethasone Pharmacology

Dexamethasone has numerous possible indications such as asthma, chemotherapy-induced nausea and vomiting, and pain associated with inflammation.

Dexamethasone is more potent than prednisone. Approximately 0.75 mg of dexamethasone is equivalent to 5 mg of prednisone.

When using dexamethasone, recall that it can raise blood sugars. Monitor this closely in patients with diabetes.

A dexamethasone suppression test helps detect excessive endogenous production of cortisol.

I discuss important drug interactions on the podcast, be sure to check out my latest project which is a 200+ page book on managing drug interactions in primary care.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

Budesonide Formoterol Pharmacology

Budesonide and Formoterol Pharmacology

Budesonide/formoterol inhalation is sold under the brand name Symbicort.

Budesonide/formoterol is a combination agent that is used in the management of COPD and asthma.

Budesonide/formoterol is a combination of an inhaled corticosteroid and long-acting beta-agonist.

GINA guidelines now allow for the use of budesonide/formoterol in the management of acute asthma exacerbation.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!