Tag: bph

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Dutasteride (Avodart) Pharmacology Podcast

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Dutasteride (Avodart) is a 5-alpha-reductase inhibitor. I discuss the pharmacology, adverse effects, and drug interactions on this podcast.

Dutasteride reduces the size of the prostate over time. It takes a significant amount of time to provide symptom relief (usually at least 3-6 months).

Dutasteride is broken down by CYP3A4 to a minor extent which means that strong CYP3A4 inhibitors may increase drug concentrations.

When using dutasteride for BPH, remember to review the medication list for drugs that can cause urinary retention such as anticholintiercs and alpha-agonists.

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Tamsulosin Pharmacology

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On this episode of the RLP podcast, I discuss tamsulosin pharmacology.

Tamsulosin inhibits alpha receptors which helps improve urine flow in patients with BPH.

As an off-label use, you may see tamsulosin used to try to aid in the passage of renal stones.

Tamsulosin concentrations may be increased by CYP3A4 inhibitors and reduced by CYP3A4 inducers.

I discuss important drug interactions on the podcast, be sure to check out my latest project which is a 200+ page book on managing drug interactions in primary care.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Finasteride Pharmacology

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On this episode of the RLP podcast, I discuss finasteride pharmacology.

Finasteride can be used in the management of BPH or male pattern baldness.

By reducing overall androgen burden, finasteride can help to shrink the prostate and improve BPH symptoms.

Finasteride takes a long time to work, so this is an important education point for patients.

I discuss important drug interactions on the podcast, be sure to check out my latest project which is a 200+ page book on managing drug interactions in primary care.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!