Tag: asthma

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Asthma Pharmacotherapy Q&A With Beth Zerr, PharmD, BCACP

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On this very special episode of the Real Life Pharmacology podcast, we tackle asthma pharmacotherapy and some of the things that Beth sees in her everyday practice as an ambulatory care pharmacist.

When discussing asthma pharmacotherapy with pediatric patients and their families, it is critical to address the concern of suppressed growth with corticosteroid use. Beth shares her expertise and thoughts on this topic.

The GINA update a few years ago has been a game changer in asthma, hear from Beth how this has been implemented in her practice.

Beth also discusses some of the everyday drug interactions and adverse effects of asthma medications in this podcast episode.

Neither Beth nor I have any conflicts of interest in regard to discussing these medications.

If you’d like to contact Beth, you can reach out to her at zerr@arizona.edu

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Prednisolone Pharmacology

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I mentioned prednisolone to prednisone conversion in this podcast. Please go check out Pyrls.com for a free steroid conversion downloadable PDF with a free account!

On this episode, I discuss prednisolone (Orapred, Pediapred) pharmacology, adverse effects, practice pearls, and drug interactions.

Prednisolone is a systemic corticosteroid that can cause insomnia, elevations in blood sugars, and numerous effects if used long-term.

CYP3A4 is an important enzyme in the breakdown of prednisolone. Inhibitors or inducers may raise or lower drug levels respectively.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

Support The Podcast and Check Out These Amazing Resources!

NAPLEX Study Materials

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Pharmacy Technician Study Guide by Meded101

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Inhaled Budesonide Pharmacology

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On this episode of the podcast, I cover budesonide (Pulmicort) pharmacology. Our sponsor (Pyrls.com/rlp) for this episode is providing a FREE PDF of their inhaled corticosteroid categorizations chart (i.e. low/medium/high dose ICS) when you sign up for a free account!

The onset of action of inhaled budesonide is several hours up to a few days. Patient education is critical to ensure that patients stick with its use.

Budesonide does have a nebulized formulation that is often used in pediatrics and geriatrics.

There aren’t a ton of critical drug interactions, but you should think about medications that inhibit CYP3A4 and may have additive immunosuppressive effects.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Salmeterol (Serevent) Pharmacology

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In this episode, I cover salmeterol (Serevent) pharmacology, adverse effects, drug interactions and special warnings with this medication.

Salmeterol is a long acting beta agonist that can be used in combination with inhaled corticosteroids for management of asthma.

Salmeterol can be used as monotherapy in COPD and should not be used as monotherapy in asthma.

Elevations in pulse and blood pressure can happen with a beta agonist like salmeterol.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

Support The Podcast and Check Out These Amazing Resources!

NAPLEX Study Materials

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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Pharmacy Technician Study Guide by Meded101

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Budesonide Formoterol Pharmacology

Budesonide and Formoterol Pharmacology

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Budesonide/formoterol inhalation is sold under the brand name Symbicort.

Budesonide/formoterol is a combination agent that is used in the management of COPD and asthma.

Budesonide/formoterol is a combination of an inhaled corticosteroid and long-acting beta-agonist.

GINA guidelines now allow for the use of budesonide/formoterol in the management of acute asthma exacerbation.

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Montelukast Pharmacology

Montelukast Pharmacology

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On this episode, I discuss montelukast pharmacology

Montelukast is a leukotriene receptor antagonist. Leukotrienes play an important role in causing inflammation and smooth muscle contraction in asthma and allergic rhinitis.

Because montelukast blocks the effects of leukotrienes, it can be advantageous to use this medication for allergies and asthma.

It is important to remind patients that montelukast is NOT a substitute for an acute relief medication like albuterol in the management of asthma symptoms.

Montelukast has been reported to cause mood and behavioral changes and it is important to monitor our patients for these rare concerns.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!