Tag: anemia

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Vitamin B12 Pharmacology

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On this episode, I cover clinical tips and practice pearls surrounding vitamin B12 pharmacology.

Vitamin B12 deficiency plays a critical role in the development of macrocytic anemia.

There are medications that you have to be aware that can deplete vitamin B12. Metformin, colchicine, and PPIs are some common examples.

A lack of intrinsic factor can lead to B12 deficiency. Intrinsic factor is necessary for adequate GI absorption of vitamin B12.

I discuss important drug interactions on the podcast, be sure to check out my latest project which is a 200+ page book on managing drug interactions in primary care.

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Epoetin Alfa Pharmacology

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Epoetin alfa is essential exogenous erythropoetin which can stimulate the production of red blood cells.

It is critical to ensure adequate iron stores when using EPO.

Risks for blood clots, strokes and heart attacks are critical to recognize with the use of epoetin.

Dosage adjustments with epoetin are typically made with respect to the amount of change in hemoglobin. I discuss this further in the podcast.

I discuss important drug interactions on the podcast, be sure to check out my latest project which is a 200+ page book on managing drug interactions in primary care.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Iron Supplement Pharmacology

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Iron supplements frequently cause GI upset. Monitor patients for nausea, vomiting, and constipation issues.

There are three main salt forms of iron. Ferrous fumurate has the most elemental iron, ferrous sulfate (2nd most), and ferrous gluconate has the least.

Iron can bind up antibiotics and reduce their effectiveness. Two classic examples include the quinolone and tetracycline antibiotics.

Anemia can be caused by numerous concerns, however, iron deficiency is a very common cause.

Ferritin is a lab that we commonly monitor in a patient who may be iron deficient. Iron deficiency can also lead to symptoms of Restless Leg Syndrome.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!