Top 200 Drugs Pharmacology Podcast – Drugs 26-30

On this episode of the Top 200 Drugs pharmacology podcast, I cover fluticasone nasal spray, allopurinol, alendronate, famotidine, and cefdinir.

Fluticasone is a corticosteroid that can be used nasally for the treatment of allergic rhinitis.

Allopurinol is a xanthine oxidase inhibitor used to reduce uric acid and prevent gout flares.

Alendronate is a bisphosphonate that inhibits the action of osteoclasts. This action helps treat osteoporosis.

Famotidine is a histamine-2 receptor antagonist that helps reduce gastric acid secretion and alleviate heartburn symptoms.

Cefdinir is a third-generation cephalosporin that is often used as an alternative for those who cannot take penicillin antibiotics. There is a small risk for cross-reactivity that a clinician has to consider.

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Alendronate Pharmacology

Alendronate is a bisphosphonate that is used in the management of osteoporosis.

In this episode, I discuss osteonecrosis risk and what are some of the risk factors that may increase the chances of this very rare adverse effect.

Binding interactions are so critical with alendronate. They can essentially make the drug useless.

Esophageal irritation and ulceration is one of the possible complications with the use of alendronate.

I discuss important drug interactions on the podcast, be sure to check out my latest project which is a 200+ page book on managing drug interactions in primary care.

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