Tag: adverse effects

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September 28, 2023September 20, 2023

Enalapril Pharmacology Podcast

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On this episode, I discuss enalapril pharmacology, adverse effects, drug interactions, and much more!

Enalapril has a shorter half-life compared to some of the other ACE inhibitors so it may need to be dosed twice daily in patients with adequate renal function.

Hyperkalemia, cough, renal impairment, and angioedema and four adverse effects associated with enalapril that you should monitor for.

NSAIDs and diuretics can increase the risk of acute renal failure when an ACE inhibitor like enalapril is being used.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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September 21, 2023September 21, 2023

Asthma Pharmacotherapy Q&A With Beth Zerr, PharmD, BCACP

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On this very special episode of the Real Life Pharmacology podcast, we tackle asthma pharmacotherapy and some of the things that Beth sees in her everyday practice as an ambulatory care pharmacist.

When discussing asthma pharmacotherapy with pediatric patients and their families, it is critical to address the concern of suppressed growth with corticosteroid use. Beth shares her expertise and thoughts on this topic.

The GINA update a few years ago has been a game changer in asthma, hear from Beth how this has been implemented in her practice.

Beth also discusses some of the everyday drug interactions and adverse effects of asthma medications in this podcast episode.

Neither Beth nor I have any conflicts of interest in regard to discussing these medications.

If you’d like to contact Beth, you can reach out to her at zerr@arizona.edu

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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September 14, 2023September 9, 2023

Lisdexamfetamine Pharmacology Podcast

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On this podcast episode, I discuss lisdexamfetamine (Vyvanse) pharmacology, adverse effects, drug interactions, and much more.

Lisdexamfetamine is a stimulant medication that is used in the management of ADHD.

Stimulants like lisdexamfetamine can increase heart rate, raise blood pressure, and suppress appetite.

Lisdexamfetamine is a schedule 2 controlled substance and has a high potential for abuse and dependence.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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August 31, 2023August 29, 2023

Insulin Lispro (Humalog) Pharmacology Podcast

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On this podcast episode, I discuss the pharmacology, adverse effects, and drug interactions of insulin lispro (Humalog).

I spend some time on this podcast episode discussing carb ratios and sliding scale insulin when using insulin lispro.

Potassium is critical to monitor in diabetic ketoacidosis as insulin therapy can cause significant hypokalemia.

Sliding-scale insulin lispro is discouraged in the overwhelming majority of situations. Ideally, we should be more proactive about insulin administration to reduce the risk of hyperglycemia spikes.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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August 24, 2023August 20, 2023

Pregabalin Pharmacology Podcast

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On this podcast episode, I discuss (Lyrica) pregabalin pharmacology, adverse effects, drug interactions, and much more.

I compare pregabalin and gabapentin in this episode and one important difference is the percent absorption of gabapentin compared to pregabalin.

Pregabalin can exacerbate the risk of respiratory depression and overdose in patients who are taking opioids.

Pregabalin is most frequently used in practice for neuropathic pain syndromes.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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August 17, 2023August 9, 2023

Tamoxifen Pharmacology Podcast

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On this podcast episode, I discuss tamoxifen pharmacology, adverse effects, drug interaction, and much more.

Tamoxifen is converted to a more active compound in the body by CYP2D6.

CYP2D6 inhibitors such as paroxetine, fluoxetine, or bupropion can essentially reduce the effectiveness of tamoxifen.

Hot flashes are a common adverse effect of tamoxifen and I discuss a few pharmacologic options to manage this adverse effect.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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August 10, 2023July 25, 2023

Phenobarbital Pharmacology Podcast

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On this episode of the Real Life Pharmacology Podcast, I cover phenobarbital pharmacology, adverse effects, important drug interactions and much more.

Phenobarbital is an enzyme inducer. It is an inducer at CYP3A4 so this can lead to numerous drug interactions.

Phenobarbital can exacerbate the risk for opioid overdose and increase the risk for respiratory depression and death.

Phenobarbital can deplete numerous vitamins such as vitamin D, folic acid, and vitamin B12. Monitoring of these is important.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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August 3, 2023July 20, 2023

Isotretinoin Pharmacology Podcast

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On this episode, I discuss isotretinoin pharmacology, side effects, drug interactions, and much more.

The iPLEDGE program is in place to ensure that pregnant patients do not receive this medication. I discuss this in more detail on this episode.

Sun sensitivity is an important adverse effect that patients should be aware of during seasons of high sun exposure.

Hepatic issues, myalgia, and psychiatric changes are rare adverse effects associated with isotretinoin.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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July 27, 2023July 19, 2023

Lovastatin Pharmacology Podcast

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On this episode of the Real Life Pharmacology Podcast, I discuss lovastatin pharmacology, adverse effect, drug interactions, and more!

Lovastatin is broken down by CYP3A4 so drugs like clarithromycin, diltiazem, and others may increase concentrations.

Lovastatin is a lipophilic statin and I discuss the importance of this on the podcast.

Lovastatin has a very short half-life which means that it is ideal to dose this medication at night for maximal efficacy.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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