Tag: adverse effects

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October 12, 2023October 6, 2023

Spironolactone Pharmacology Podcast

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On this episode, I discuss spironolactone pharmacology, adverse effects, drug interactions and much more.

Spironolactone has numerous indications including hypertension, CHF, ascites, and acne. I break them all down in this podcast episode.

Hyperkalemia is a major concern with spironolactone. Patients with baseline levels at 5 or above should generally avoid this medication.

Gynecomastia is one of the most commonly tested adverse effects of spironolactone. Be sure you don’t miss this one on your board and pharmacology exams!

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October 5, 2023October 2, 2023

Meloxicam Pharmacology Podcast

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I discuss meloxicam pharmacology, adverse effects, drug interactions, and much more on this episode of the Real Life Pharmacology Podcast.

Meloxicam tends to have a greater affinity to COX-2 versus COX-1. I discuss what this means clinically on this episode.

Important meloxicam drug interactions include anticoagulants, antiplatelet medications, renal impairing drugs, and lithium amongst others.

Meloxicam has a longer half-life than many NSAIDs and because of this can be dosed once daily for pain relief.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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September 28, 2023September 20, 2023

Enalapril Pharmacology Podcast

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On this episode, I discuss enalapril pharmacology, adverse effects, drug interactions, and much more!

Enalapril has a shorter half-life compared to some of the other ACE inhibitors so it may need to be dosed twice daily in patients with adequate renal function.

Hyperkalemia, cough, renal impairment, and angioedema and four adverse effects associated with enalapril that you should monitor for.

NSAIDs and diuretics can increase the risk of acute renal failure when an ACE inhibitor like enalapril is being used.

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September 21, 2023September 21, 2023

Asthma Pharmacotherapy Q&A With Beth Zerr, PharmD, BCACP

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On this very special episode of the Real Life Pharmacology podcast, we tackle asthma pharmacotherapy and some of the things that Beth sees in her everyday practice as an ambulatory care pharmacist.

When discussing asthma pharmacotherapy with pediatric patients and their families, it is critical to address the concern of suppressed growth with corticosteroid use. Beth shares her expertise and thoughts on this topic.

The GINA update a few years ago has been a game changer in asthma, hear from Beth how this has been implemented in her practice.

Beth also discusses some of the everyday drug interactions and adverse effects of asthma medications in this podcast episode.

Neither Beth nor I have any conflicts of interest in regard to discussing these medications.

If you’d like to contact Beth, you can reach out to her at zerr@arizona.edu

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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September 14, 2023September 9, 2023

Lisdexamfetamine Pharmacology Podcast

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On this podcast episode, I discuss lisdexamfetamine (Vyvanse) pharmacology, adverse effects, drug interactions, and much more.

Lisdexamfetamine is a stimulant medication that is used in the management of ADHD.

Stimulants like lisdexamfetamine can increase heart rate, raise blood pressure, and suppress appetite.

Lisdexamfetamine is a schedule 2 controlled substance and has a high potential for abuse and dependence.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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August 31, 2023August 29, 2023

Insulin Lispro (Humalog) Pharmacology Podcast

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On this podcast episode, I discuss the pharmacology, adverse effects, and drug interactions of insulin lispro (Humalog).

I spend some time on this podcast episode discussing carb ratios and sliding scale insulin when using insulin lispro.

Potassium is critical to monitor in diabetic ketoacidosis as insulin therapy can cause significant hypokalemia.

Sliding-scale insulin lispro is discouraged in the overwhelming majority of situations. Ideally, we should be more proactive about insulin administration to reduce the risk of hyperglycemia spikes.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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August 24, 2023August 20, 2023

Pregabalin Pharmacology Podcast

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On this podcast episode, I discuss (Lyrica) pregabalin pharmacology, adverse effects, drug interactions, and much more.

I compare pregabalin and gabapentin in this episode and one important difference is the percent absorption of gabapentin compared to pregabalin.

Pregabalin can exacerbate the risk of respiratory depression and overdose in patients who are taking opioids.

Pregabalin is most frequently used in practice for neuropathic pain syndromes.

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August 17, 2023August 9, 2023

Tamoxifen Pharmacology Podcast

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On this podcast episode, I discuss tamoxifen pharmacology, adverse effects, drug interaction, and much more.

Tamoxifen is converted to a more active compound in the body by CYP2D6.

CYP2D6 inhibitors such as paroxetine, fluoxetine, or bupropion can essentially reduce the effectiveness of tamoxifen.

Hot flashes are a common adverse effect of tamoxifen and I discuss a few pharmacologic options to manage this adverse effect.

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