Top 200 Drugs – Medications 181-185

On this Real Life Pharmacology Podcast episode, we cover medications 181-185.

Proscar is the brand name for finasteride. This medication can be helpful in shrinking the size of the prostate but it does typically take a while to work (months).

Sinemet is a combination of carbidopa and levodopa. Levodopa is converted in the central nervous system to dopamine to help alleviate a shortage of dopamine in the brain.

Risedronate is a bisphosphonate medication that can be used in the treatment of osteoporosis.

Albuterol (Ventolin) is a short-acting beta-agonist that is used to relieve symptoms of acute respiratory distress most often associated with an asthma exacerbation.

Tramadol is classified as an opioid analgesic. It also has activity similar to SNRIs as it has the ability to increase serotonin and norepinephrine in the brain.

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Top 200 Drugs – Medications 176-180

Prednisolone is a corticosteroid that is often used in pediatrics. Hyperglycemia, insomnia, and GI upset are relatively common adverse effects.

Ibuprofen is a commonly used OTC pain reliever. It is classified as an NSAID and can increase GI bleed risk and exacerbate heart failure.

Aceon is the brand name for perindopril. ACE inhibitors are well known to cause drug induced cough and will cause hyperkalemia.

Trazodone is classified as an antidepressant but is frequently used to treat insomnia because of its sedative properties.

Pioglitazone is an oral anti-diabetes medication that should be avoided in patients with heart failure.

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Top 200 Drugs – Medications 156-160

Welcome back to the Real Life Pharmacology podcast! We are on the home stretch of the top 200 medications. This is meant to be a quicker refresher of some of the most important drugs you’ll come across in practice. Please be sure to go search the archives at RealLifePharmacology.com if you are looking for more information on one specific medication. We have over 300 individual episodes on specific drugs!

On this episode of the Top 200 medications, we’ve covered the medications below.

Niaspan (niacin) is vitamin B3 and may be used in patients who fail other therapies for triglyceride management.

Uroxatral (alfuzosin) is a selective alpha-blocker that can be helpful in relieving urinary retention symptoms in BPH.

Biaxin (clarithromycin) is a macrolide antibiotic that is notorious for many drug interactions because it inhibits CYP3A4.

Zomig (zolmitriptan) is a “triptan” medication that can be used for the acute relief of migraine headaches.

Invokana (canagliflozin) was one of the first SGLT2 inhibitors invented that can be used to lower blood sugar in type 2 diabetes.

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Top 200 Drugs Podcast – Medications 131-135

On this episode of the Top 200 drugs podcast from Real Life Pharmacology, I cover medications 131-135 which include enoxaparin, methylphenidate, rosuvastatin, denosumab, and dabigatran.

Enoxaparin is an injectable anticoagulant that can cause heparin-induced thrombocytopenia.

Methylphenidate is a stimulant medication that can be used to treat ADHD. Cardiovascular adverse effects are possible.

Rosuvastatin inhibits HMG-CoA Reductase which helps lower LDL in the management of hypercholesterolemia.

Denosumab is a monoclonal antibody that is indicated for osteoporosis and may cause hypocalcemia.

Dabigatran was one of the first direct oral anticoagulants to be produced. It is dosed twice daily and has warnings about use in patients over the age of 75.

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Top 200 Drugs Podcast – Medications 126-130

In this episode of the Top 200 Drugs Podcast, we cover medications 126-130.

Trastuzumab is a monoclonal antibody that can be used for breast cancer that expresses the HER2 protein.

Atripla is an HIV medication that contains three separate medications that are beneficial in reducing viral load.

Rivaroxaban is an anticoagulant that may be commonly used in the management of stroke and deep vein thrombosis.

Fioricet is a combination of three medications. Butalbital, acetaminophen, and caffeine are the three ingredients in this medication.

Insulin detemir is a long-acting insulin analog that lowers blood sugar. This medication is used to target fasting blood sugars.

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Top 200 Drugs Podcast – Medications 121-125

On the top 200 drugs podcast, we cover 5 more medications. The medications covered on today’s episode include; omalizumab, nitroglycerin, apixaban, gabapentin, and etanercept.

Omalizumab is a monoclonal antibody used in moderate to severe asthma. It targets IgE-mediated asthma attacks and reactions. Anaphylaxis is a significant concern with the use of this medication.

Sublingual nitroglycerin is frequently used on an as needed basis for angina symptoms. I discuss major drug interactions and much more.

Apixaban is an anticoagulant used to prevent stroke in atrial fibrillation. It can also be used in DVT/PE treatment and prevention.

Gabapentin is classified as an antiepileptic agent but is most commonly used for neuropathic type pain.

Etanercept targets TNF alpha which plays an important role in autoimmune diseases such as rheumatoid arthritis.

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Top 200 Drugs Podcast – Medications 81-85

On this episode of the Real Life Pharmacology podcast, I cover medications 81 through 85 on the top 200 drug list.

Famotidine is an H2 blocker. H2 blockers are less potent than PPIs but can be used to manage heartburn symptoms.

Aspirin is technically an NSAID but is primarily used for cardioprophylaxis purposes.

Senna is a stimulant laxative. I often see this medication used with opioids to help manage opioid-induced constipation.

Novolog is a rapid acting insulin used to bring down post prandial blood sugars. I discuss sliding scale insulin and other concepts with this medication.

Baclofen is a skeletal muscle relaxant. It has central nervous system depressant effects which can be especially problematic in elderly patients.

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Top 200 Drugs Podcast – Medications 76-80

Reglan (metoclopramide) is used for gastroparesis and inhibits gastric smooth muscle by blocking dopamine receptors.

Relafen (nabumetone) is a non-selective inhibition of COX-1/COX-2 which leads to a reduction of inflammation via reduced prostaglandins.

Keflex (cephalexin) is a 1st generation oral cephalosporin that covers common gram positive organisms like Staph and Strep species.

Effexor (Venlafaxine) is an SNRI and inhibits both serotonin and norepinephrine reuptake. Primary uses include anxiety and depression.

Boniva (ibandronate) inhibits osteoclasts which helps treat osteoporosis. Osteoclasts break down bone to help pull calcium into the bloodstream.

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Top 200 Drugs Podcast – Medications 71-75

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Robitussin (Guaifenesin) is a medication that is used as a cough suppressant. It is often combined with numerous other medications so patients need to pay attention

Valium (diazepam) is a benzodiazepine used to treat anxiety or seizures. Falls, dizziness, confusion, and sedation are common adverse effects.

Viagra (sildenafil) makes the list at number 73. This medication is a PDE-5 inhibitor that can be used for erectile dysfunction.

Bactroban (mupirocin) is a topical antibiotic that can be used for superficial skin infections.

Januvia (Sitagliptin) is a DPP4 inhibitor used for treating hyperglycemia in type 2 diabetes. It doesn’t reduce A1C quite as much as other diabetes medications like SGLT2 inhibitors and GLP-1 agonists.

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Top 200 Drugs Podcast – Medications 66-70

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Pantoprazole (Protonix) is a PPI that can be used for GERD and peptic ulcer disease. I differentiate why this medication is different from the commonly used omeprazole.

Dicyclomine (Bentyl) is an anticholinergic medication that may be used to help reduce pain and spasms associated with irritable bowel syndrome.

Sumatriptan (Imitrex) is a selective 5HT1 receptor agonist, which potentially helps with vasoconstriction that contributes to migraine symptoms.

Chlorhexidine (Peridex) is an antibiotic oral rinse that can be used for gingivitis.

Metoprolol (Lopressor, Toprol XL) is a beta-blocker that may be used for atrial fibrillation, angina prevention, and hypertension. It is not a first-line medication for hypertension.

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Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!