Tag: acne

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Isotretinoin Pharmacology Podcast

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On this episode, I discuss isotretinoin pharmacology, side effects, drug interactions, and much more.

The iPLEDGE program is in place to ensure that pregnant patients do not receive this medication. I discuss this in more detail on this episode.

Sun sensitivity is an important adverse effect that patients should be aware of during seasons of high sun exposure.

Hepatic issues, myalgia, and psychiatric changes are rare adverse effects associated with isotretinoin.

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Erythromycin Pharmacology

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Erythromycin uniquely has some potential benefit in the setting of gastroparesis. Azithromycin you will likely not see used for this indication.

Erythromycin binds the 50s subunit and ultimately prevents protein synthesis which is necessary for bacteria to grow and replicate.

QTc prolongation is a risk with all macrolide antibiotics (erythromycin included).

By inhibiting CYP3A4, erythromycin can be responsible for numerous drug interactions.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!