Welcome to your Nursing Pharmacology Practice Questions – Pharmacogenomics, Kinetics, and Dynamics
Pharmacokinetics Definition
Which statement best describes pharmacokinetics?
Bioavailability Comparison
Which of the following forms of administration will always provide the highest bioavailability?
Loading Dose Purpose
What is the primary reason for a loading dose?
Administration With Slowest Onset
You'd like to drug Y quickly into the bloodstream. Which route of administration would likely take the longest?
Drug Binding
In patients with low levels of ______ in the blood, the amount free drug can significantly increase and increase the risk for adverse effects.
Elimination
What is the primary organ responsible for elimination of medications?
Example NTI Medication
Which of the following would be an example of a narrow therapeutic index medication?
Describing Drug Action
Describing how a beta-blocker has its effects on the body would be consistent with which of the following?
Allopurinol Genetic Risk
Patients who are HLA-B58:01 positive will have an increased risk of what adverse effect?
HIV Medication Assessment
Which HIV medication requires genetic testing prior to use?
Bupropion Genetic Variation
A genetic alteration in which enzyme will affect bupropion metabolism?
Warfarin Breakdown
Genetic variations in which enzyme will affect concentrations of warfarin?
Clopidogrel
A poor metabolizer at CYP2C19 will have what affect on clopidogrel?