Top 200 Drugs Podcast – Drugs 21-25

Lamotrigine is an antiseizure medication and also may be used for bipolar disorder. A rash is a major side effect to remember with this medication.

Valganciclovir is an antiviral medication that can be used to prevent cytomegalovirus (CMV) in patients with a suppressed immune system.

Fluconazole is an azole antifungal that can be used to treat candidiasis, blastomycosis, and tinea infections. Drug interactions, QTc prolongation, and hepatotoxicity are potential risks.

Atenolol is a beta-blocker used to treat atrial fibrillation and hypertension. It is relatively selective for beta-1 receptors meaning that it doesn’t affect the lungs as much as non-selective agents.

Montelukast is a medication that blocks the actions of leukotrienes. This can be beneficial for the management of allergies and asthma.

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Top 200 Drugs Pharmacology Podcast – Drugs 16-20

In this episode of the Real Life Pharmacology podcast, I cover drugs 16-20 of the top 200 drugs. This podcast includes information about clozapine, furosemide, heparin, tetracycline, and vardenafil.

Clozapine has five boxed warnings and these are all items that you may see on your pharmacology and board exams! I’ve also blogged about these in the past at meded101.

Furosemide is a loop diuretic and a common indicator of the prescribing cascade. I discuss this in this podcast episode.

Heparin can cause thrombocytopenia. I discuss what HIT (heparin-induced thrombocytopenia) may look like.

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Top 200 Drugs Pharmacology Podcast – Drugs 11-15

Metformin is a medication used in the management of diabetes. It can cause significant diarrhea, B12 deficiency, and in rare cases, lactic acidosis.

Atorvastatin (Lipitor) is a statin medication used for cholesterol management. It lowers LDL and is associated with myopathy.

Omeprazole is a PPI used for GERD and has drug interactions with citalopram and clopidogrel.

Ciprofloxacin is a quinolone antibiotic used to treat gram-negative infections and UTIs. It carries numerous risks such as tendon rupture.

Ondansetron is an antiemetic medication used in the management of nausea and vomiting. I discuss the prescribing cascade in relation to this medication.

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Top 200 Drugs 6-10 Pharmacology Podcast

On this episode of the Real Life Pharmacology podcast, I discuss drugs 6-10 of the top 200 drugs.

Included in this podcast episode are two antibiotics that are frequently used in pediatrics. Those two antibiotics are azithromycin and amoxicillin.

Alprazolam is a benzodiazepine. It is a controlled substance that is used for the acute relief of anxiety. It is not well tolerated in the elderly.

Hydrochlorothiaizde is a thiazide diuretic used primarily for hypertension. It can exacerbate gout and cause frequent urination.

Amlodipine is a dihydropyridine calcium channel blocker. The most important adverse effect to remember with this medication is edema.

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Top 200 Drugs Podcast – Drugs 1-5

On this episode of the Real Life Pharmacology Podcast, I start my journey on summarizing the most highly testable pearls with the top 200 medications. I’m going through the top 200 medications, 5 drugs at a time, and sharing my experience and clinically relevant information about these medications.

Escitalopram is an SSRI that can cause serotonin syndrome, sexual dysfunction, and SIADH.

Simvastatin is a cholesterol medication that can cause myopathy and rhabdomyolysis.

Levothyroxine is a thyroid hormone replacement medication that has numerous binding drug interactions.

Vicodin is a brand name combination of hydrocodone and acetaminophen. It is an opioid combined with and OTC analgesic.

Lisinopril is an ACE inhibitor used for hypertension that can cause a chronic dry cough and hyperkalemia.

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Timolol Pharmacology Podcast

On this episode, I discuss timolol pharmacology, adverse effects, drug interactions, and much more.

Timolol is a non-selective beta-blocker so it blocks both beta-1 and beta-2 receptors.

Since timolol blocks beta-2 receptors, it can blunt the effect of respiratory medications that have beta-agonist action.

Beta-blockers are notorious for causing bradycardia and pulse is an important monitoring parameter for timolol.

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Continuous Glucose Monitors Podcast

Continuous Glucose Monitors (CGMs) are becoming an important tool in the management of diabetes. I break down some of the most common clinical practice pearls you should know.

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Food and Supplement Drug Interactions

On this episode of the Real Life Pharmacology Podcast, I cover some of the most common food and supplement drug interactions.

The 3 G’s can potentially increase the risk of bleeding in patients on anticoagulants and antiplatelets. I discuss what supplements these are.

There are some vitamins that can cause drug interactions. Vitamin C is a supplement that can alter the absorption of some medications.

Metal cations like iron can bind certain medications and reduce absorption. I discuss which medications are most likely to be affected.

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Vonoprazan Pharmacology – New Esophagitis Medication Class! Episode 326

On this episode, I discuss the new medication vonoprazan and where it will likely be used in practice.

Vonoprazan is from a brand new class of medication called “PCAB”. I discuss this medication and its pharmacology in this podcast episode.

Drug interactions and cost are the two major downsides of this medication that will likely limit its use compared to the PPIs.

CYP3A4 inducers like rifampin, carbamazepine, and phenytoin should not be used with vonoprazan. They will reduce the effectiveness of vonoprazan.

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10 Commandments of Polypharmacy Part 2 of 2

clear plastic container and medicine capsule

Today’s sponsor of the 10 Commandments of Polypharmacy podcast is FreedAI. Freed listens, transcribes, and writes medical documentation for you.

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Here is part 2 of 2 on the final 5 of the 10 commandments of polypharmacy.

6. Thou shalt identify limits for medications not intended for chronic use as well as not continue a medication indefinitely for symptoms that have an expected short duration

7. Thou shalt not start a medication from a similar medication class without appropriate rationale

8. Thou shalt not initiate a medication without considering medications that may treat duplicate conditions – Kill two birds with one stone

9. Thou shalt consider eliminating or reducing medications at every medication review

10. Thou shalt be willing to accept risk in discontinuing a medication if they were willing to accept the risk of initiating a medication

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