Top 200 Drugs Podcast – Medications 71-75

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Robitussin (Guaifenesin) is a medication that is used as a cough suppressant. It is often combined with numerous other medications so patients need to pay attention

Valium (diazepam) is a benzodiazepine used to treat anxiety or seizures. Falls, dizziness, confusion, and sedation are common adverse effects.

Viagra (sildenafil) makes the list at number 73. This medication is a PDE-5 inhibitor that can be used for erectile dysfunction.

Bactroban (mupirocin) is a topical antibiotic that can be used for superficial skin infections.

Januvia (Sitagliptin) is a DPP4 inhibitor used for treating hyperglycemia in type 2 diabetes. It doesn’t reduce A1C quite as much as other diabetes medications like SGLT2 inhibitors and GLP-1 agonists.

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Top 200 Drugs Podcast – Medications 66-70

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Pantoprazole (Protonix) is a PPI that can be used for GERD and peptic ulcer disease. I differentiate why this medication is different from the commonly used omeprazole.

Dicyclomine (Bentyl) is an anticholinergic medication that may be used to help reduce pain and spasms associated with irritable bowel syndrome.

Sumatriptan (Imitrex) is a selective 5HT1 receptor agonist, which potentially helps with vasoconstriction that contributes to migraine symptoms.

Chlorhexidine (Peridex) is an antibiotic oral rinse that can be used for gingivitis.

Metoprolol (Lopressor, Toprol XL) is a beta-blocker that may be used for atrial fibrillation, angina prevention, and hypertension. It is not a first-line medication for hypertension.

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Top 200 Drugs Podcast – Medications 61-65

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In this episode, we highlight some of the most important clinical pearls (and highly testable pearls) on the following medications; Suboxone, lisdexamfetamine, nortriptyline, insulin lispro, and valproic acid.

Suboxone is a combination of buprenorphine and naloxone used for opioid use disorder.

Lisdexamfetamine is a stimulant medication that can be used to manage ADHD. Common side effects include weight loss, insomnia, hypertension, and tachycardia.

Nortriptyline is a TCA medication known for its ability to cause anticholinergic side effects like constipation, dry eyes, dry mouth, urinary retention, and confusion.

Insulin lispro is a rapid-acting insulin medication that is most often used to bring down post-prandial blood sugar.

Valproic acid is an antiepileptic medication that can also be used for migraines.

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Top 200 Drugs Podcast – Medications 56-60

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In this episode, we highlight some of the most important clinical pearls on the following medications; nitrofurantoin, fentanyl patches, isosorbide mononitrate, fluoxetine, and triamcinolone.

Nitrofurantoin is an antibiotic used for UTIs. We need to be careful with this medication in patients with CKD.

Fentanyl is an opioid. There are many clinical quirks with fentanyl patches. For a full rundown, check out this previous podcast episode.

Isosorbide mononitrate is a nitrate medication so we need to be careful with the use of PDE-5 inhibitors.

Fluoxetine is an SSRI. It has a longer half-life than most SSRIs. I discuss what that means in this episode.

Triamcinolone (topical) is most frequently used for redness, itching, and skin irritation.

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Top 200 Drugs – Medications 51-55

On this episode of the Real Life Pharmacology podcast, I cover medications 51-55. They are eszopiclone, celecoxib, estrogen, moxifloxacin, and donepezil.

Eszopiclone is a “Z” drug used for insomnia. Its adverse effect profile is very similar to benzodiazepines.

Celecoxib is a COX-2 Inhibitor used for pain and inflammation. I discuss how this medication differs from traditional NSAIDs.

Estrogen therapy is used for menopausal symptoms but carries a risk of cancer and blood clots.

Moxifloxacin is a quinolone antibiotic. Binding drug interactions, boxed warnings, and QTc prolongation are potential concerns.

Donepezil is a medication used for dementia. I discuss its mechanism of action and common adverse effects.

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Top 200 Drugs Podcast – Drugs 46-50

On this episode, we continue with the Top 200 Drugs podcast. We cover the basics of the following drugs: tizanidine, risperidone, ramipril, pravastatin, and terazosin.

Tizanidine is a skeletal muscle relaxant that has drug interactions via CYP2D6

Risperidone is a 2nd generation antipsychotic. Be on the lookout for EPS, hyperprolactinemia, sedation, and metabolic syndrome.

Ramipril is an antihypertensive agent that is an ACE Inhibitor. Cough and hyperkalemia are two important adverse effects.

Pravastatin is an HMG-CoA reductase inhibitor that lowers LDL levels. It isn’t as potent as other statins and I discuss this on the podcast episode.

Terazosin is a non-selective alpha-blocker that may be used for BPH and hypertension.

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Top 200 Drugs Podcast – Drugs 41-45

On this episode of the Real Life Pharmacology podcast, I continue my education on the top 200 drugs. Raloxifene, prednisone, phenytoin, fish oil, and ezetimibe are covered in this podcast episode.

Prednisone is a corticosteroid that may cause hyperglycemia, insomnia, GI upset, osteoporosis, HPA suppression, and hypertension as primary adverse effects.

Raloxifene is classified as a SERM and can be used for osteoporosis and breast cancer. DVT and hot flashes are significant adverse effect concerns.

Fish oil (Lovaza) is used to reduce triglycerides. Elevated triglycerides can increase the risk of pancreatitis.

Ezetimibe inhibits the absorption of cholesterol through the gut. It lowers LDL but not to the extent of statins.

Phenytoin is a narrow therapeutic index medication (NTI) that is used as an anticonvulsant. Ataxia, confusion, GI upset, and vertical nystagmus are potential signs of toxicity.

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Top 200 Drugs Podcast – Drugs 36-40

On this episode of the Real Life Pharmacology podcast, I continue my coverage with the Top 200 Drugs Podcast. Here’s the list of medications we will cover.

  • Lorazepam (Ativan) is a benzodiazepine well known for its anxiolytic and anti-seizure properties.
  • Phenazopyridine (Pyridium) is a urinary analgesic that can change the color of the urine to a reddish/orange color as one of its adverse effects.
  • Hydroxychloroquine (Plaquenil) is a DMARD used in rheumatoid arthritis and Lupus. One highly testable and unique nugget to remember is that it can cause retinopathy.
  • Lidocaine patch (Lidoderm) is used topically to help with various types of pain including neuropathy and postherpetic neuralgia.
  • Diclofenac (Cataflam) is an NSAID used as an analgesic and anti-inflammatory. It can increase the risk of GI bleed, edema, renal failure, and thrombosis.

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Top 200 Drugs Podcast – Drugs 31-35

On this episode of the Real Life Pharmacology podcast, I discuss drugs 31-35 of the top 200 drugs.

Ethinyl estradiol/drospirenone is a combined oral contraceptive used for birth control purposes.

Hydralazine is a direct vasodilatory that can be used for hypertension and heart failure.

Benztropine is an older anticholinergic medication originally indicated for Parkinson’s disease but most commonly used to manage EPS symptoms from dopamine-blocking agents such as antipsychotics.

Tussionex is a combination medication of chlorpheniramine and hydrocodone. It is used to help alleviate cough.

Paroxetine is an SSRI used for the treatment of depression, anxiety, and other psychiatric disorders.

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Top 200 Drugs Pharmacology Podcast – Drugs 26-30

On this episode of the Top 200 Drugs pharmacology podcast, I cover fluticasone nasal spray, allopurinol, alendronate, famotidine, and cefdinir.

Fluticasone is a corticosteroid that can be used nasally for the treatment of allergic rhinitis.

Allopurinol is a xanthine oxidase inhibitor used to reduce uric acid and prevent gout flares.

Alendronate is a bisphosphonate that inhibits the action of osteoclasts. This action helps treat osteoporosis.

Famotidine is a histamine-2 receptor antagonist that helps reduce gastric acid secretion and alleviate heartburn symptoms.

Cefdinir is a third-generation cephalosporin that is often used as an alternative for those who cannot take penicillin antibiotics. There is a small risk for cross-reactivity that a clinician has to consider.

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