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December 30, 2021January 10, 2022

Lasmiditan Pharmacology

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Lasmiditan (Reyvow) is an agent that is utilized for acute migraine treatment. It works slightly differently than triptans which I discuss on this episode.

Lasmiditan is a relatively new agent and cost will often limit its use at this time.

Rosuvastatin and sulfasalazine are two common medications that may have concentrations increase when lasmiditan is used. I discuss this in detail on this episode.

Lasmiditan is an oral tablet that is only recommended to give once per day which differs from commonly used triptans where the dose can be repeated.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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December 23, 2021January 10, 2022

Sumatriptan Pharmacology

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On this episode, I discuss sumatriptan pharmacology, adverse effects, drug interactions and more.

Dosage forms can provide different methods of drug delivery and I talk about many different sumatriptan dosage forms in this episode.

Cardiovascular risks need to be assessed when using a drug like sumatriptan. I discuss this in greater detail in the podcast.

Sumatriptan has serotonergic activity and we need to assess the risk of serotonin syndrome in our patients.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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December 16, 2021January 10, 2022

Bumetanide Pharmacology

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On this episode of the Real Life Pharmacology Podcast, I discuss bumetanide pharmacology, adverse effects, and drug interactions.

Bumetanide is a loop diuretic and it is critical to monitor renal function and electrolytes with this medication.

Ototoxicity is a rare adverse effect that is dose-dependent and can be worsened by aminoglycosides.

It is critical to look for drugs that can worsen edema when using bumetanide to ensure that we avoid the prescribing cascade.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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December 9, 2021January 10, 2022

Oxycodone Pharmacology

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On this episode, I discuss oxycodone pharmacology, adverse effect, pharmacokinetics, and drug interactions.

Oxycodone is broken down by CYP3A4 and CYP2D6. I discuss this further on the podcast and how interactions may alter concentrations.

When a patient stops taking oxycodone after being on it for some time, you must recognize common symptoms of withdrawal.

Oxycodone comes as in an extended-release and immediate-release oral formulation.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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November 25, 2021January 10, 2022

Doxycycline Pharmacology

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On this episode of the Real Life Pharmacology podcast, I explore doxycycline pharmacology, adverse effects, and drug interactions.

Doxycycline can be bound by numerous minerals like calcium, magnesium, and iron. Coadministration can lead to reduced concentrations.

Sun sensitivity is a really important adverse effect that can be caused by doxycycline. Be sure to educate your patients.

Doxycycline can be used as an alternative to beta-lactams and macrolides in the management of community-acquired pneumonia.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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November 18, 2021January 11, 2022

Tolterodine Pharmacology

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On this episode, I discuss tolterodine pharmacology, adverse effects, and drug interactions.

Tolterodine (Detrol) is an anticholinergic medication used to manage the symptoms of overactive bladder.

Tolterodine’s anticholinergic activity can lead to a significant number of adverse effects like dry mouth, dry eyes, constipation, and urinary retention.

Elderly patients may be at greater risk for anticholinergic adverse effects from tolterodine compared to younger patients.

Tolterodine can have additive effects from other anticholinergics like diphenhydramine or TCAs which enhance its potential for side effects.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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November 11, 2021January 10, 2022

Clarithromycin Pharmacology

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On this episode, I discuss clarithromycin pharmacology, adverse effects, and drug interactions.

Clarithromycin is a macrolide antibiotic that can be used for many similar indications as azithromycin.

Clarithromycin has numerous drug interactions as it can inhibit CYP3A4. This limits its use in practice.

Clarithromycin can be used in the treatment of H. pylori in combination with other antibiotics and a PPI.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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November 4, 2021January 10, 2022

Azathioprine Pharmacology

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On this episode, I discuss azathioprine pharmacology, adverse effects, monitoring parameters, and drug interactions.

Azathioprine is classified as an immunosuppressive agent so it is naturally going to be used for autoimmune type disorders and transplantation.

Azathioprine has a boxed warning for myelosuppression. I talk more about this in the episode.

Genetic testing is recommended by the AGA prior to the use of azathioprine. I discuss which tests might be helpful to reduce the risk of toxicity.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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October 28, 2021January 10, 2022

Amitriptyline Pharmacology

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On this episode, I discuss amitriptyline pharmacology, adverse effects, and drug interactions.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

Support The Podcast and Check Out These Amazing Resources!

Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)