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Buspirone is an anti-anxiety medication that has the potential of having some serotonin agonist activity.
Buspirone has a very high first-pass metabolism. This means that the body breaks much of the medication down prior to it getting into the systemic circulation.
Buspirone is broken down by CYP3A4, so concomitant use with inhibitors or inducers can alter its concentrations
Buspirone should not be used as needed as this medication takes a while to start to show benefit.
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